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Reconstructing SNP allele and genotype frequencies from GWAS summary statistics

Abstract The emergence of genome-wide association studies (GWAS) has led to the creation of large repositories of human genetic variation, creating enormous opportunities for genetic research and worldwide collaboration. Methods that are based on GWAS summary statistics seek to leverage such records...

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Main Authors: Zhiyu Yang, Peristera Paschou, Petros Drineas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2022-05-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-022-12185-6
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