Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population

<p>Abstract</p> <p>The development and progression of colorectal cancer (CRC) is a multi-step process, and the Wnt pathways with its two molecular gladiators adenomatous polyposis coli (<it>APC</it>) and <it>β-catenin </it>plays an important role in transfor...

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Bibliographic Details
Main Authors: Sameer A, Shah Zaffar A, Abdullah Safiya, Chowdri Nissar A, Siddiqi Mushtaq A
Format: Artigo
Language:Inglês
Published: BMC 2011-07-01
Series:Human Genomics
Subjects:
Wnt pathway
APC
β-catenin
colorectal cancer
Kashmir
hypermethylation
mutations
Dukes' stage
Online Access:http://www.humgenomics.com/content/5/5/441
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