RNA-binding protein hnRNPR reduces neuronal cholesterol levels by binding to and suppressing HMGCR

Recent studies have identified multiple RNA-binding proteins tightly associated with lipid and neuronal cholesterol metabolism and cardiovascular disorders. However, the role of heterogeneous nuclear ribonucleoprotein R (hnRNPR) in cholesterol metabolism and homeostasis, whether it has a role in...

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Autori principali: John Agbo, Akinsola Raphael Akinyemi, Dingfeng Li, Qingyang Zhang, Xiaohui Li, Wenbo Li, Juan Zhang, Qiang Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: IMR Press 2021-06-01
Serie:Journal of Integrative Neuroscience
Soggetti:
heterogeneous nuclear ribonucleoprotein
3-hydroxy-3-methyl-glutaryl-coenzyme a reductase
neuronal cholesterol biosynthesis
neuroblastoma cell
mn1 cell
rna metabolism
Accesso online:https://jin.imrpress.com/fileup/1757-448X/PDF/1625014726269-1554335725.pdf
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