PRRSV Vaccine Strain-Induced Secretion of Extracellular ISG15 Stimulates Porcine Alveolar Macrophage Antiviral Response against PRRSV

Porcine reproductive and respiratory syndrome virus (PRRSV) has disrupted the global swine industry since the 1980s. PRRSV-host interactions are largely still unknown but may involve host ISG15 protein. In this study, we developed a monoclonal antibody (Mab-3D5E6) specific for swine ISG15 (sISG15) b...

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Detalhes bibliográficos
Main Authors: Hongbin Liu, Bingjun Shi, Zhigang Zhang, Bao Zhao, Guangming Zhao, Yijing Li, Yuchen Nan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-09-01
Colecção:Viruses
Assuntos:
interferons
PRRSV
ISG15
macrophage
interferons-stimulated genes
cytokine
Acesso em linha:https://www.mdpi.com/1999-4915/12/9/1009
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