Proteomics analysis: inhibiting the expression of P62 protein by chloroquine combined with dacarbazine can reduce the malignant progression of uveal melanoma

Abstract Background Although uveal melanoma (UM) at the early stage is controllable to some extent, it inevitably ultimately leads to death due to its metastasis. At present, the difficulty is that there is no way to effectively tackle the metastasis. It is hypothesized that these will be treated by...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xifeng Fei, Xiangtong Xie, Ruwei Qin, Anqi Wang, Xuan Meng, Fei Sun, Yifan Zhao, Dongyi Jiang, Hanchun Chen, Qiang Huang, Xiaoyan Ji, Zhimin Wang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:BMC Cancer
Assuntos:
Orthotopic and ectopic transplantation models of uveal melanoma
Transgenic EGFP nude mice
Differential proteomics and bioinformatics analysis
p62 protein
Chloroquine
Dacarbazine
Acesso em linha:https://doi.org/10.1186/s12885-022-09499-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados