Aucuba japonica extract inhibits retinal neovascularization in a mouse model of oxygen‐induced retinopathy, with its bioactive components preventing VEGF‐induced retinal vascular hyperpermeability

Abstract Neovascularization in the retina is common pathophysiology of diabetic retinal microvasculopathy and exudative macular degeneration. Our study assessed the inhibitory activity of an ethanol‐based extract of Aucuba japonica (AJE) on abnormal angiogenesis in the retina with a hyperoxia‐induce...

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Main Authors: Eunsoo Jung, Woo Kwon Jung, Su‐Bin Park, Hyung Rae Kim, Junghyun Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-06-01
Colecção:Food Science & Nutrition
Assuntos:
angiogenesis
Aucuba japonica
functional food
retinal neovascularization
Acesso em linha:https://doi.org/10.1002/fsn3.1590
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