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A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype.
Cardiac Na(+) channels encoded by the SCN5A gene are essential for initiating heart beats and maintaining a regular heart rhythm. Mutations in these channels have recently been associated with atrial fibrillation, ventricular arrhythmias, conduction disorders, and dilated cardiomyopathy (DCM).We inv...
Gorde:
Egile Nagusiak: | , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Public Library of Science (PLoS)
2012-01-01
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Saila: | PLoS ONE |
Sarrera elektronikoa: | http://europepmc.org/articles/PMC3365008?pdf=render |
Etiketak: |
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