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The Evolution of Imprinted microRNAs and Their RNA Targets

Mammalian genomes contain many imprinted microRNAs. When an imprinted miRNA targets an unimprinted mRNA their interaction may have different fitness consequences for the loci encoding the miRNA and mRNA. In one possible outcome, the mRNA sequence evolves to evade regulation by the miRNA by a simple...

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Autores principales: David Haig, Avantika Mainieri
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-09-01
Colección:Genes
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Acceso en línea:https://www.mdpi.com/2073-4425/11/9/1038
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