Secreted Frizzled Related Protein 2 Modulates Epithelial–Mesenchymal Transition and Stemness via Wnt/β-Catenin Signaling in Choriocarcinoma

Background/Aims: Choriocarcinoma (CC) is a highly aggressive gestational trophoblastic neoplasia; however, the underlying molecular mechanisms of its invasiveness and metastasis remain poorly understood. Human secreted frizzled-related protein 2 (SFRP2) could function as a tumor promoter or suppress...

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Detalhes bibliográficos
Main Authors: Xianling Zeng, Yafei Zhang, Huiqiu Xu, Taohong Zhang, Yan Xue, Ruifang An
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
Secreted frizzled related protein 2
Epithelial–mesenchymal transition
Stemness
Wnt/β-catenin
Choriocarcinoma
Acesso em linha:https://www.karger.com/Article/FullText/494862
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