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Trabectedin – the DNA minor groove binder
Trabectedin (ET-743, Yondelis) is an alkaloid that was originally isolated from the Caribbean Sea squirt, Ecteinascidia turbinata and is now produced synthetically. Its chemical structure consists in three fused tetrahydroisoquinoline rings. Two of them, A and B, binds covalently to guanine residues...
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Main Authors: | , , , |
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Formáid: | Artigo |
Teanga: | Russo |
Foilsithe: |
ABV-press
2015-06-01
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Sraith: | Uspehi Molekulârnoj Onkologii |
Ábhair: | |
Rochtain Ar Líne: | https://umo.abvpress.ru/jour/article/view/24 |
Clibeanna: |
Cuir Clib Leis
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