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Prevalence of Transcriptionally Active HPV Infection in Tumor-Free Oropharyngeal Tissue of OPSCC-Patients

ObjectivesThe natural history of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) is still largely unknown. Since reports of second primary tumors (SPTs) in patients with HPV-related OPSCCs are increasing, a multifocal HPV infection, hinting a «virus-induced field effect», has been hypothes...

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Auteurs principaux: Vittoria Guarda, Lea Schroeder, Michael Pawlita, Kristian Ikenberg, Niels J. Rupp, Wolfram Jochum, Sandro J. Stoeckli, Dana Holzinger, Martina A. Broglie
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-04-01
Collection:Frontiers in Oncology
Sujets:
head and neck cancer
oropharynx cancer
human papillomavirus
second primary neoplasms
human papillomavirus DNA tests
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fonc.2022.835814/full
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