Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents

<p>Abstract</p> <p>Background</p> <p>Methotrexate treatment has been associated to intestinal epithelial damage. Studies have suggested an important role of nitric oxide in such injury. The aim of this study was to investigate the role of nitric oxide (NO), specifically...

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Detaylı Bibliyografya
Asıl Yazarlar: Siqueira Francisco JWS, Lima-Júnior Roberto CP, Gomes Antoniella S, Silva Johann V, Bellaguarda Emmanuelle AL, Braga-Neto Manuel B, Oriá Reinaldo B, Brito Gerly AC, Leitão Renata FC, Freire Rosemeyre S, Vale Mariana L, Ribeiro Ronaldo A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2011-08-01
Seri Bilgileri:BMC Gastroenterology
Konular:
Nitric oxide
Nitric oxide synthase
Methotrexate
Aminoguanidine
Nφ-Nitro-L-arginine methyl ester
Online Erişim:http://www.biomedcentral.com/1471-230X/11/90
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