Development of a Comprehensive HPLC Method for Determination of Product-related Impurities and Assay of Active Ingredients in Papaverine Hydrochloride Products

Abstract. Papaverine hydrochloride products are used as anticonvulsants in routine medical practice. Most of the approved product specification files include thin-layer chromatography for assessment of product-related impurities and UV spectrophotometry for determination of active pharmaceutical ing...

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Main Authors: N. P. Antonova, E. P. Shefer, N. E. Semenova, S. S. Prokhvatilova, A. M. Kalinin, S. A. Kuchugurin, V. N. Makukhin
Formato: Artigo
Idioma:Russo
Publicado em: OOO “Vashe Tsifrovoe Izdatelstvo” 2021-03-01
Colecção:Ведомости Научного центра экспертизы средств медицинского применения
Assuntos:
papaverine hydrochloride
hplc
spectrophotometry
pharmacopoeial tests
solution for injection
tablets
rectal suppositories
Acesso em linha:https://www.vedomostincesmp.ru/jour/article/view/314
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