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Leptin Regulates Tau Phosphorylation through Wnt Signaling Pathway in PC12 Cells
Background/Aims: Leptin, an adipocytokine produced endogenously in the brain, is decreased in Alzheimer's disease(AD) and has also been shown to reduce Aβ levels in vitro and in vivo. Sets of evidence show that leptin reduces Aβ production and tau phosphorylation in neuronal cells and transgeni...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cell Physiol Biochem Press GmbH & Co KG
2016-10-01
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Colecção: | Neurosignals |
Assuntos: | |
Acesso em linha: | http://www.karger.com/Article/FullText/442616 |
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