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Leptin Regulates Tau Phosphorylation through Wnt Signaling Pathway in PC12 Cells

Background/Aims: Leptin, an adipocytokine produced endogenously in the brain, is decreased in Alzheimer's disease(AD) and has also been shown to reduce Aβ levels in vitro and in vivo. Sets of evidence show that leptin reduces Aβ production and tau phosphorylation in neuronal cells and transgeni...

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Detalhes bibliográficos
Main Authors: Zijuan Zhang, Meixia Guo, Juan Zhang, Caixia Du, Ying Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2016-10-01
Colecção:Neurosignals
Assuntos:
Wnt
Tau
Acesso em linha:http://www.karger.com/Article/FullText/442616
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