TGF-β1 is Involved in Vitamin D-Induced Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Regulating the ERK/JNK Pathway

Background/Aims: Osteoarthritis (OA) is characterized by degradation of cartilage, sole cell type of which is chondrocytes. Bone marrow-derived mesenchymal stem cells (BMSCs) possess multipotency and can be directionally differentiated into chondrocytes under stimulation. This study was aimed to exp...

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Autors principals: Xiaorui Jiang, Botao Huang, Huiying Yang, Guishi Li, Chunlei Zhang, Guangshi Yang, Feng Lin, Guodong Lin
Format: Artigo
Idioma:Inglês
Publicat: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Col·lecció:Cellular Physiology and Biochemistry
Matèries:
Osteoarthritis
BMSC
Vitamin D
TGF-β1
Chondrogenic differentiation
ERK/JNK pathway
Accés en línia:http://www.karger.com/Article/FullText/479997
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