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The transcription factor REST is lost in aggressive breast cancer.

The function of the tumor suppressor RE1 silencing transcription factor (REST) is lost in colon and small cell lung cancers and is known to induce anchorage-independent growth in human mammary epithelial cells. However, nothing is currently known about the role of this tumor suppressor in breast can...

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Главные авторы: Matthew P Wagoner, Kearney T W Gunsalus, Barry Schoenike, Andrea L Richardson, Andreas Friedl, Avtar Roopra
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2010-06-01
Серии:PLoS Genetics
Online-ссылка:http://europepmc.org/articles/PMC2883591?pdf=render
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