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The transcription factor REST is lost in aggressive breast cancer.

The function of the tumor suppressor RE1 silencing transcription factor (REST) is lost in colon and small cell lung cancers and is known to induce anchorage-independent growth in human mammary epithelial cells. However, nothing is currently known about the role of this tumor suppressor in breast can...

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Autori principali: Matthew P Wagoner, Kearney T W Gunsalus, Barry Schoenike, Andrea L Richardson, Andreas Friedl, Avtar Roopra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-06-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC2883591?pdf=render
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