Clinico-Immunological Profile of a 67-Year-Old Woman Affected by HER2-Positive Breast Cancer and Autoimmune Dermatomyositis

A patient with HER2-positive early breast cancer (BC) developed dermatomyositis (DM), which disappeared after the first administration of adjuvant trastuzumab. No HER2 overexpression/amplification was observed in DM skin biopsies. Both BC and skin immune infiltrates were composed mostly of CD3+ T-ly...

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Detalhes bibliográficos
Main Authors: Benedetta Pellegrino, Giulia Mazzaschi, Denise Madeddu, Cristina Mori, Costanza Anna Maria Lagrasta, Gabriele Missale, Federico Quaini, Antonino Musolino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
Colecção:Frontiers in Oncology
Assuntos:
breast cancer
HER2
dermatomyositis
trastuzumab
autoimmune
cross-reactivity
Acesso em linha:https://www.frontiersin.org/article/10.3389/fonc.2020.00192/full
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