Kinetic Characterization of 100 Glycoside Hydrolase Mutants Enables the Discovery of Structural Features Correlated with Kinetic Constants.

The use of computational modeling algorithms to guide the design of novel enzyme catalysts is a rapidly growing field. Force-field based methods have now been used to engineer both enzyme specificity and activity. However, the proportion of designed mutants with the intended function is often less t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dylan Alexander Carlin, Ryan W Caster, Xiaokang Wang, Stephanie A Betzenderfer, Claire X Chen, Veasna M Duong, Carolina V Ryklansky, Alp Alpekin, Nathan Beaumont, Harshul Kapoor, Nicole Kim, Hosna Mohabbot, Boyu Pang, Rachel Teel, Lillian Whithaus, Ilias Tagkopoulos, Justin B Siegel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science (PLoS) 2016-01-01
श्रृंखला:PLoS ONE
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC4729467?pdf=render
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