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Two-Pore Channels Regulate Inter-Organellar Ca<sup>2+</sup> Homeostasis in Immune Cells

Two-pore channels (TPCs) are ligand-gated cation-selective ion channels that are preserved in plant and animal cells. In the latter, TPCs are located in membranes of acidic organelles, such as endosomes, lysosomes, and endolysosomes. Here, we focus on the function of these unique ion channels in mas...

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Detalhes bibliográficos
Main Authors: Philip Steiner, Elisabeth Arlt, Ingrid Boekhoff, Thomas Gudermann, Susanna Zierler
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Cells
Assuntos:
TPC
Acesso em linha:https://www.mdpi.com/2073-4409/11/9/1465
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