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Delineating the role of osteoprotegerin as a marker of breast cancer risk among women with a BRCA1 mutation

Abstract Women with a pathogenic germline mutation in the BRCA1 gene face a very high lifetime risk of developing breast cancer, estimated at 72% by age 80. Prophylactic bilateral mastectomy is the only effective way to lower their risk; however, most women with a mutation opt for intensive screenin...

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Detalhes bibliográficos
Main Authors: Sarah Sohyun Park, Aleksandra Uzelac, Joanne Kotsopoulos
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Hereditary Cancer in Clinical Practice
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Acesso em linha:https://doi.org/10.1186/s13053-022-00223-3
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