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Delineating the role of osteoprotegerin as a marker of breast cancer risk among women with a BRCA1 mutation
Abstract Women with a pathogenic germline mutation in the BRCA1 gene face a very high lifetime risk of developing breast cancer, estimated at 72% by age 80. Prophylactic bilateral mastectomy is the only effective way to lower their risk; however, most women with a mutation opt for intensive screenin...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2022-04-01
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Colecção: | Hereditary Cancer in Clinical Practice |
Assuntos: | |
Acesso em linha: | https://doi.org/10.1186/s13053-022-00223-3 |
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