Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis

Abstract Background The risks of harms from opioids increase substantially at high doses, and high-dose prescribing has increased in primary care. However, little is known about what leads to high-dose prescribing, and studies exploring this have not been synthesized. We, therefore, systematically s...

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Detalhes bibliográficos
Main Authors: Georgia C. Richards, Kamal R. Mahtani, Tonny B. Muthee, Nicholas J. DeVito, Constantinos Koshiaris, Jeffrey K. Aronson, Ben Goldacre, Carl J. Heneghan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-03-01
Colecção:BMC Medicine
Assuntos:
Opioids
High dose
Primary care
Systematic review
Benzodiazepines
Depression
Acesso em linha:http://link.springer.com/article/10.1186/s12916-020-01528-7
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