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Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester

<p>Abstract</p> <p>Background</p> <p>Classical bioconjugation strategies for generating antibody-functionalized nanoparticles are non-specific and typically result in heterogeneous compounds that can be compromised in activity. Expression systems based on self-cleavable...

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Main Authors: Raats Jos MH, van Baal Ingrid, Reulen Sanne WA, Merkx Maarten
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2009-07-01
Sraith:BMC Biotechnology
Rochtain Ar Líne:http://www.biomedcentral.com/1472-6750/9/66
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