CUBN as a novel locus for end-stage renal disease: insights from renal transplantation.

Chronic kidney disease (CKD) is a complex disorder. As genome-wide association studies identified cubilin gene CUBN as a locus for albuminuria, and urinary protein loss is a risk factor for progressive CKD, we tested the hypothesis that common genetic variants in CUBN are associated with end-stage r...

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Autors principals: Anna Reznichenko, Harold Snieder, Jacob van den Born, Martin H de Borst, Jeffrey Damman, Marcory C R F van Dijk, Harry van Goor, Bouke G Hepkema, Jan-Luuk Hillebrands, Henri G D Leuvenink, Jan Niesing, Stephan J L Bakker, Marc Seelen, Gerjan Navis, REGaTTA (REnal GeneTics TrAnsplantation) Groningen group
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3344899?pdf=render
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