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Analysis of the expression of normal and mutant full⁃length atrophin⁃1 gene in stable and transient transfected eukaryotic cell line

Objective To establish eukaryotic expression system of full ⁃ length gene in normal [CAG repeats (Q19)] and abnormal [CAG repeats (Q82 and Q66)] atrophin ⁃ 1 [the pathogenic gene of dentatorubral⁃pallidoluysian atrophy (DRPLA)]. To compare the expression system of stable and transient transfected ce...

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Detalhes bibliográficos
Main Authors: Xin ZHANG, Weihong GU, Guoxiang WANG
Formato: Artigo
Idioma:Inglês
Publicado em: Tianjin Huanhu Hospital 2011-02-01
Colecção:Chinese Journal of Contemporary Neurology and Neurosurgery
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Acesso em linha:http://www.cjcnn.org/index.php/cjcnn/article/view/318
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