Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis

Abstract Background Radiation-induced oral mucositis (OM) is one of the most common acute complications for head and neck cancer. Severe OM is associated with radiation treatment breaks, which harms successful tumor management. Radiogenomics studies have indicated that genetic variants are associate...

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Bibliografski detalji
Glavni autori: Da-Wei Yang, Tong-Min Wang, Jiang-Bo Zhang, Xi-Zhao Li, Yong-Qiao He, Ruowen Xiao, Wen-Qiong Xue, Xiao-Hui Zheng, Pei-Fen Zhang, Shao-Dan Zhang, Ye-Zhu Hu, Guo-Ping Shen, Mingyuan Chen, Ying Sun, Wei-Hua Jia
Format: Artigo
Jezik:Inglês
Izdano: BMC 2020-06-01
Serija:Journal of Translational Medicine
Teme:
Radiation injuries
Oral mucositis
Radiogenomics
Genome-wide association study
Functional mapping
Online pristup:http://link.springer.com/article/10.1186/s12967-020-02390-0
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