Probiotic-derived heptelidic acid exerts antitumor effects on extraintestinal melanoma through glyceraldehyde-3-phosphate dehydrogenase activity control

Abstract Background Several microorganisms inhabit the mammalian gastrointestinal tract and are associated with the pathogenesis of various diseases, including cancer. Recent studies have indicated that several probiotics produce antitumor molecules and inhibit host tumor progression. We demonstrate...

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Main Authors: Shotaro Isozaki, Hiroaki Konishi, Hiroki Tanaka, Chikage Yamamura, Kentaro Moriichi, Naoki Ogawa, Mikihiro Fujiya
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-04-01
Series:BMC Microbiology
Assuntos:
Glyceraldehyde-3-phosphate dehydrogenase
Heptelidic acid
Melanoma
Acceso en liña:https://doi.org/10.1186/s12866-022-02530-0
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