Development of thyroid dysfunction is associated with clinical response to PD-1 blockade treatment in patients with advanced non-small cell lung cancer

Purpose: Drugs that blockade interaction between programmed cell-death protein 1 (PD-1) and its ligand (PD-L1) are promising. Immune-related adverse events (irAEs) might be associated with favorable clinical outcomes, and thyroid dysfunction is one of the most common irAE. We evaluated the associati...

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Main Authors: Hye In Kim, Mijin Kim, Se-Hoon Lee, So Young Park, Young Nam Kim, Hosu Kim, Min Ji Jeon, Tae Yong Kim, Sun Wook Kim, Won Bae Kim, Sang-We Kim, Dae Ho Lee, Keunchil Park, Myung-Ju Ahn, Jae Hoon Chung, Young Kee Shong, Won Gu Kim, Tae Hyuk Kim
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2018-01-01
Series:OncoImmunology
Subjects:
biomarkers
immunotherapy
non-small cell lung cancer
programmed cell death 1
thyroid
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1375642
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