Dexamethasone inhibits the HSV-<it>tk</it>/ ganciclovir bystander effect in malignant glioma cells

<p>Abstract</p> <p>Background</p> <p>HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. Large studies have however failed to demonstrate any significant benefit of this strategy...

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Bibliographic Details
Main Authors: Jolois Olivier, Nguyen-Khac Minh, Robe Pierre A, Rogister Bernard, Merville Marie-Paule, Bours Vincent
Format: Artigo
Language:Inglês
Published: BMC 2005-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/32
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