ロード中...
Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain
The use of siRNA-based therapies for the treatment of neurodegenerative disease requires efficient, nontoxic distribution to the affected brain parenchyma, notably the striatum and cortex. Here, we describe the synthesis and activity of a fully chemically modified siRNA that is directly conjugated t...
保存先:
| 主要な著者: | , , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2016-01-01
|
| シリーズ: | Molecular Therapy: Nucleic Acids |
| 主題: | |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S2162253117300677 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|