Low dose of extracellular vesicles identified that promote recovery after ischemic stroke

Abstract Background Mesenchymal stem cell-derived extracellular vesicles (EVs) are one of the most promising therapeutics in protective and/or regenerative therapy in animal models of stroke using a dose of 100 μg. However, whether EVs dose is related to outcomes is not known. This study aimed to id...

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Detalhes bibliográficos
Main Authors: Laura Otero-Ortega, Fernando Laso-García, Mari Carmen Gómez-de Frutos, Luke Diekhorst, Arturo Martínez-Arroyo, Elisa Alonso-López, María Laura García-Bermejo, Macarena Rodríguez-Serrano, Mercedes Arrúe-Gonzalo, Exuperio Díez-Tejedor, Blanca Fuentes, María Gutiérrez-Fernández
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-02-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Brain repair
Extracellular vesicles
Oxygen and glucose deprivation
Subcortical stroke
White matter lesion
Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01601-1
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