Cell Death Mechanisms Induced by CLytA-DAAO Chimeric Enzyme in Human Tumor Cell Lines

The combination of the choline binding domain of the amidase N-acetylmuramoyl-L-alanine (CLytA)-D-amino acid oxidase (DAAO) (CLytA-DAAO) and D-Alanine induces cell death in several pancreatic and colorectal carcinoma and glioblastoma cell lines. In glioblastoma cell lines, CLytA-DAAO-induced cell de...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: María Fuentes-Baile, Pilar García-Morales, Elizabeth Pérez-Valenciano, María P. Ventero, Jesús M. Sanz, Camino de Juan Romero, Víctor M. Barberá, Cristina Alenda, Miguel Saceda
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-11-01
Serija:International Journal of Molecular Sciences
Teme:
cancer therapy
reactive oxygen species
oxidative damage
mitochondrial membrane potential
calcium mobilization
PARP-1
Online dostop:https://www.mdpi.com/1422-0067/21/22/8522
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki