FRET Visualization of Cyclic Stretch-Activated ERK via Calcium Channels Mechanosensation While Not Integrin β1 in Airway Smooth Muscle Cells

Mechanical stretch is one type of common physiological activities such as during heart beating, lung breathing, blood flow through the vessels, and physical exercise. The mechanical stimulations regulate cellular functions and maintain body homeostasis. It still remains to further characterize the m...

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Main Authors: Xin Fang, Kai Ni, Jia Guo, Yaqin Li, Ying Zhou, Hui Sheng, Bing Bu, Mingzhi Luo, Mingxing Ouyang, Linhong Deng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Assuntos:
cyclic stretch
mechanosensation
ERK
calcium channel
fluorescence resonance energy transfer
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcell.2022.847852/full
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