Gene set signature of reversal reaction type I in leprosy patients.

Leprosy reversal reactions type 1 (T1R) are acute immune episodes that affect a subset of leprosy patients and remain a major cause of nerve damage. Little is known about the relative importance of innate versus environmental factors in the pathogenesis of T1R. In a retrospective design, we evaluate...

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Hauptverfasser: Marianna Orlova, Aurélie Cobat, Nguyen Thu Huong, Nguyen Ngoc Ba, Nguyen Van Thuc, John Spencer, Yohann Nédélec, Luis Barreiro, Vu Hong Thai, Laurent Abel, Alexandre Alcaïs, Erwin Schurr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS Genetics
Online Zugang:http://europepmc.org/articles/PMC3708838?pdf=render
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