Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries

Therapeutic antibodies must have “drug-like” properties. These include high affinity and specificity for the intended target, biological activity, and additional characteristics now known as “developability properties”: long-term stability and resistance to aggregation when in solution, thermodynami...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Andre Azevedo Reis Teixeira, Michael Frank Erasmus, Sara D’Angelo, Leslie Naranjo, Fortunato Ferrara, Camila Leal-Lopes, Oliver Durrant, Cecile Galmiche, Aleardo Morelli, Anthony Scott-Tucker, Andrew Raymon Morton Bradbury
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2021-01-01
Colecção:mAbs
Assuntos:
Antibody
phage display
yeast display
developability
antibody discovery
antibody therapeutics
Acesso em linha:https://www.tandfonline.com/doi/10.1080/19420862.2021.1980942
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados