Computationally efficient permutation-based confidence interval estimation for tail-area FDR

Challenges of satisfying parametric assumptions in genomic settings with thousands or millions of tests have led investigators to combine powerful False Discovery Rate (FDR) approaches with computationally expensive but exact permutation testing. We describe a computationally efficient permutation-b...

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Main Authors: Joshua eMillstein, Dmitri eVolfson
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013-09-01
Serier:Frontiers in Genetics
Fag:
Gene Expression
Sleep
multiple testing
false discovery rates
simultaneous inference
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00179/full
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