Glycyrrhiza uralensis Fisch. and its active components mitigate Semen Strychni-induced neurotoxicity through regulating high mobility group box 1 (HMGB1) translocation

Semen Strychni has long been used for the treatment of rheumatoid arthritis, facioplegia and myasthenia gravis due to its anti-inflammation and anti-nociceptive properties in China. However, the fatal neurotoxicity of Semen Strychni has limited its wider clinical application. To investigate the acut...

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Detalhes bibliográficos
Main Authors: Xiaoyu Duan, Jing Wen, Min Zhang, Chao Wang, Yalan Xiang, Lu Wang, Changwei Yu, Gongying Deng, Miao Yan, Bikui Zhang, Pingfei Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-05-01
Colecção:Biomedicine & Pharmacotherapy
Assuntos:
Semen Strychni
Neurotoxicity
Liquorice
Neuroprotection
HMGB1
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0753332222002736
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