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Efficient Palladium-Catalyzed Synthesis of 2-Aryl Propionic Acids

A flexible two-step, one-pot procedure was developed to synthesize 2-aryl propionic acids including the anti-inflammatory drugs naproxen and flurbiprofen. Optimal results were obtained in the presence of the novel ligand neoisopinocampheyldiphenylphosphine (NISPCPP) (<b>9</b>) which enab...

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Hlavní autoři: Helfried Neumann, Alexey G. Sergeev, Anke Spannenberg, Matthias Beller
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-07-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/25/15/3421
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