DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Abstract Recent technological advances have enabled DNA methylation to be assayed at single-cell resolution. However, current protocols are limited by incomplete CpG coverage and hence methods to predict missing methylation states are critical to enable genome-wide analyses. We report DeepCpG, a com...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Christof Angermueller, Heather J. Lee, Wolf Reik, Oliver Stegle
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2017-04-01
Edice:Genome Biology
Témata:
Deep learning
Artificial neural network
Machine learning
Single-cell genomics
DNA methylation
Epigenetics
On-line přístup:http://link.springer.com/article/10.1186/s13059-017-1189-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky