DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Por Christof Angermueller, Heather J. Lee, Wolf Reik, Oliver Stegle
Publicado em 2017-04-01

Etoposide induces nuclear re-localisation of AID.

Por Laurens J Lambert, Simon Walker, Jack Feltham, Heather J Lee, Wolf Reik, Jonathan Houseley
Publicado em 2013-01-01

Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

Por Diljeet Gill, Aled Parry, Fátima Santos, Hanneke Okkenhaug, Christopher D Todd, Irene Hernando-Herraez, Thomas M Stubbs, Inês Milagre, Wolf Reik
Publicado em 2022-04-01

Processive DNA demethylation via DNA deaminase-induced lesion resolution.

Por Don-Marc Franchini, Chun-Fung Chan, Hugh Morgan, Elisabetta Incorvaia, Gopinath Rangam, Wendy Dean, Fatima Santos, Wolf Reik, Svend K Petersen-Mahrt
Publicado em 2014-01-01

Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.

Por Raffaella Nativio, Kerstin S Wendt, Yoko Ito, Joanna E Huddleston, Santiago Uribe-Lewis, Kathryn Woodfine, Christel Krueger, Wolf Reik, Jan-Michael Peters, Adele Murrell
Publicado em 2009-11-01

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

Por Oliver Hahn, Sebastian Grönke, Thomas M. Stubbs, Gabriella Ficz, Oliver Hendrich, Felix Krueger, Simon Andrews, Qifeng Zhang, Michael J. Wakelam, Andreas Beyer, Wolf Reik, Linda Partridge
Publicado em 2017-03-01

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

Por Hisham Mohammed, Irene Hernando-Herraez, Aurora Savino, Antonio Scialdone, Iain Macaulay, Carla Mulas, Tamir Chandra, Thierry Voet, Wendy Dean, Jennifer Nichols, John C. Marioni, Wolf Reik
Publicado em 2017-08-01