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Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy
Abstract Background Signal transducer and activator of transcription 3 (STAT3) is an oncogene, which upregulates in approximately 70% of human cancers. Autophagy is an evolutionarily conserved process which maintains cellular homeostasis and eliminates damaged cellular components. Moreover, the STAT...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
BMC
2019-07-01
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叢編: | Journal of Experimental & Clinical Cancer Research |
主題: | |
在線閱讀: | http://link.springer.com/article/10.1186/s13046-019-1303-z |
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