Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease

Tumor necrosis factor (TNF) alpha is a major proinflammatory cytokine involved in the immune response in inflammatory bowel disease (IBD). Anti-TNF drugs such as infliximab and adalimumab are used to treat IBD; however, approximately 30% of patients do not respond to treatment. Individual genetic di...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rocío Prieto-Pérez, Berta Almoguera, Teresa Cabaleiro, Hakon Hakonarson, Francisco Abad-Santos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2016-02-01
Cyfres:International Journal of Molecular Sciences
Pynciau:
inflammatory bowel disease
polymorphisms
pharmacogenomics
adalimumab
infliximab
Mynediad Ar-lein:http://www.mdpi.com/1422-0067/17/2/225
Tagiau: Ychwanegu Tag
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