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Highly efficient rDNA‐mediated multicopy integration based on the dynamic balance of rDNA in Saccharomyces cerevisiae

Summary Engineered Saccharomyces cerevisiae strains are good cell factories, and developing additional genetic manipulation tools will accelerate construction of metabolically engineered strains. Highly repetitive rDNA sequence is one of two main sites typically used for multicopy integration of gen...

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Hauptverfasser: Huihui Zheng, Kai Wang, Xiaoxiao Xu, Jing Pan, Xinhua Sun, Jin Hou, Weifeng Liu, Yu Shen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2022-05-01
Schriftenreihe:Microbial Biotechnology
Online Zugang:https://doi.org/10.1111/1751-7915.14010
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