COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

<p>Abstract</p> <p>Background</p> <p>Inducible cyclooxgenase-2 (COX-2) is commonly overexpressed in breast tumors and is a target for cancer therapy. Here, we studied the association of COX-2 with breast cancer survival and how this association is influenced by tumor es...

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Detalhes bibliográficos
Main Authors: Goodman Julie E, Wink David A, Dorsey Tiffany M, Boersma Brenda J, Ridnour Lisa A, Prueitt Robyn L, Glynn Sharon A, Yfantis Harris G, Lee Dong H, Ambs Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2010-11-01
Colecção:BMC Cancer
Acesso em linha:http://www.biomedcentral.com/1471-2407/10/626
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