The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) perform paracrine functions by releasing extracellular vesicles (EVs) containing microRNA, mRNA, and proteins. We investigated the mRNA content of EVs in metabolic syndrome (MetS) and tested hypothesis that comorbidities interfere with the paracrine...

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Detalhes bibliográficos
Main Authors: Yu Meng, Alfonso Eirin, Xiang-Yang Zhu, Daniel R. O’Brien, Amir Lerman, Andre J. van Wijnen, Lilach O. Lerman
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-07-01
Colecção:Diabetology & Metabolic Syndrome
Assuntos:
Mesenchymal stem cells
Extracellular vesicles
mRNA
Metabolic syndrome
Swine
Acesso em linha:http://link.springer.com/article/10.1186/s13098-018-0359-9
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