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SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob miceResearch in context
Background: Sirtuin 5 (SIRT5) is a NAD+-dependent lysine deacylase. The SIRT5 deficiency mouse model shows that it is dispensable for metabolic homeostasis under normal conditions. However, the biological role of SIRT5 and acylation in pathological states such as obesity and type 2 diabetes (T2D) re...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018-10-01
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| Colecção: | EBioMedicine |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2352396418303955 |
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