Crosstalk in competing endogenous RNA networks reveals new circular RNAs involved in the pathogenesis of early HIV infection

Abstract Background The events in early HIV infection (EHI) are important determinants of disease severity and progression rate to AIDS, but the mechanisms of pathogenesis in EHI have not been fully understood. Circular RNAs (circRNAs) have been verified as “microRNA sponges” that regulate gene expr...

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Main Authors: Yue Zhang, Hui Zhang, Minghui An, Bin Zhao, Haibo Ding, Zining Zhang, Youwen He, Hong Shang, Xiaoxu Han
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-11-01
Colecção:Journal of Translational Medicine
Assuntos:
HIV-1
circRNA
ceRNA
Viral replication
Acesso em linha:http://link.springer.com/article/10.1186/s12967-018-1706-1
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