LXR Agonist Regulates the Carcinogenesis of PCa via the SOCS3 Pathway

Background: Down-regulation of suppressor of cytokine signaling 3 (SOCS3) inhibits prostate cancer (PCa) cell growth. Liver X receptors (LXRs) agonists have been recently introduced for PCa treatment. We postulated that LXR may inhibit the carcinogenesis of PCa via the SOCS3 pathway. Methods: LNCaP...

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Detalhes bibliográficos
Main Authors: Weihua Fu, Jiwei Yao, Yan Huang, Qianwei Li, Weibing Li, Zhiwen Chen, Fengtian He, Zhansong Zhou, Junan Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
Tumorgenesis
Prostate cancer
Suppressor of cytokine signaling 3
Liver X receptors
Small-interfering RNA
Acesso em linha:http://www.karger.com/Article/FullText/356662
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