Osteopontin promotes rat hepatocyte proliferation both in vitro and in vivo

Aim This study aimed to examine the effects of osteopontin (OPN) on hepatocyte growth and liver regeneration (LR).Methods A recombinant lentivirus expressing OPN and OPN-siRNAs were used to treat BRL-3A cells, while the adenovirus expressing OPN or OPN-targeted shRNA were applied for rat primary hep...

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Autori principali: Gaiping Wang, Peipei Chu, Meng Chen, Liya Cheng, Congcong Zhao, Shasha Chen, Xiaofang Li, Ganggang Yang, Cuifang Chang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2019-12-01
Serie:Artificial Cells, Nanomedicine, and Biotechnology
Soggetti:
Osteopontin
BRL-3A
primary hepatocyte
hepatocyte proliferation
liver regeneration
Accesso online:https://www.tandfonline.com/doi/10.1080/21691401.2019.1666862
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