The Synergistic Effect of Tacrolimus (FK506) or Everolimus and Azoles Against Scedosporium and Lomentospora Species In Vivo and In Vitro

Scedosporium and Lomentospora infections in humans are generally chronic and stubborn. The use of azoles alone cannot usually inhibit the growth of these fungi. To further explore the combined effect of multiple drugs and potential mechanisms of action, we tested the antifungal effects of tacrolimus...

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Hlavní autoři: Zikuo Wang, Mei Liu, Luyao Liu, Linyun Li, Lihua Tan, Yi Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-04-01
Edice:Frontiers in Cellular and Infection Microbiology
Témata:
Immunocompromised adults
Azoles
Tacrolimus
Everolimus
Scedosprium
On-line přístup:https://www.frontiersin.org/articles/10.3389/fcimb.2022.864912/full
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